It showed that there was insufficient formation of the endocardial cushion.
2.
These thickenings are called endocardial cushions.
3.
Endocardial cushion defects are associated with abnormalities of the atrioventricular valves ( the mitral valve and the tricuspid valve ).
4.
In some Nkx2.5 mutants, the cardiac tube is formed but the endocardial cushions and trabeculae are absent.
5.
After the development of the SAN, the superior endocardial cushions begin to form a pacemaker as known as the atrioventricular node.
6.
Notch signaling is involved early in the formation of the endocardial cushions and continues to be active as the develop into the septa and valves.
7.
Heart defects commonly seen with Ritscher-Schinzel syndrome are associated with the endocardial cushion and are the most important factor in determining a diagnosis.
8.
"ERBB3 " is expressed in the mesenchyme of the endocardial cushion, which will later develop into the valves of the heart.
9.
The atrial canal is in turn divided into a right and left side by the atrioventricular septum, which originates from the union of the dorsal and ventral endocardial cushion.
10.
Upon sectioning of the heart the atrioventricular endocardial cushions can be observed in the lumen of the atrial canal as two thickenings, one on its dorsal and another on its ventral wall.
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